Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea.
Clin Nucl Med. 2011 Aug;36(8):e87-9. doi: 10.1097/RLU.0b013e318217ae58.
A 67-year-old man with back pain was diagnosed as having multiple spinal metastases on MRI. On CT scan, only a filling defect in the right pulmonary artery was observed and suspected as venous thromboembolism. On F-18 fluorodeoxyglucose (FDG) PET/CT, intense hypermetabolism was observed in the right pulmonary artery in addition to the metastatic spine lesions. Biopsy confirmed the lesion as a primary pulmonary artery sarcoma (PAS), and the spine lesions as metastases of PAS. Although PAS is rare and its bone metastasis presenting initial symptom is extremely rare, FDG PET/CT is an effective diagnostic modality for PAS, not only in discrimination from venous thromboembolism, but also in workup of metastatic origin.
一位 67 岁男性,因背痛,MRI 诊断为多发性脊柱转移瘤。CT 扫描仅观察到右肺动脉充盈缺损,疑为静脉血栓栓塞症。在 F-18 氟脱氧葡萄糖(FDG)PET/CT 上,除了转移的脊柱病变外,还观察到右肺动脉代谢明显增高。活检证实病变为肺动脉原发性肉瘤(PAS),脊柱病变为 PAS 的转移。虽然 PAS 罕见,其以骨转移为首发症状更是罕见,但 FDG PET/CT 是一种有效的 PAS 诊断方法,不仅可用于与静脉血栓栓塞症相鉴别,还可用于寻找转移灶的来源。