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[利用电子自旋共振自旋捕获技术研究香烟烟雾气相中的自由基]

[Free radicals in gasphase of cigarette smoke by electron spin resonance spin trapping technic].

作者信息

Zhao B

出版信息

Zhonghua Yi Xue Za Zhi. 1990 Jul;70(7):386-8, 28.

PMID:2171730
Abstract

The free radicals in gasphase of cigarette smoke were determined by use of spin trapping agents PBN (N-tert-butyl-2-phenyl nitrone) and DMPO (5,5-dimethyl-1-pyrroline-1-oxide) on electron spin resonance (ESR) spectrometer. The free radicals were identified according to the spectrum parameters calculated from the spectra. The free radicals mainly consist of alkoxyl and alkyl free radicals, of which alkoxyl free radicals make up 60-70% of the total spectral component. There are a few of other unidentified free radicals. These free radicals are very active and reactive. They can damage cells and lead to some diseases. This will play an important role in scavenging the free radicals and in preventing some diseases caused by the free radicals of cigarette smoke.

摘要

利用自旋捕获剂PBN(N-叔丁基-2-苯基硝酮)和DMPO(5,5-二甲基-1-吡咯啉-1-氧化物),在电子自旋共振(ESR)光谱仪上测定香烟烟雾气相中的自由基。根据从光谱计算出的光谱参数鉴定自由基。自由基主要由烷氧基自由基和烷基自由基组成,其中烷氧基自由基占总光谱成分的60%-70%。还有一些其他未鉴定的自由基。这些自由基非常活跃且具有反应性。它们会损害细胞并导致一些疾病。这对于清除自由基以及预防由香烟烟雾自由基引起的一些疾病将发挥重要作用。

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