GW Medical Faculty Associates, Division of Pulmonary, Critical Care, and Sleep Medicine, George Washington University Hospital, Washington, DC, USA.
Ann N Y Acad Sci. 2011 Jun;1228:46-58. doi: 10.1111/j.1749-6632.2011.06075.x.
Sarcoidosis is a multisystem granulomatous disorder that most commonly presents with pulmonary involvement. The diagnosis is suggested on the basis of clinical and radiologic manifestations and is supported by the histological demonstration of noncaseating granulomas in affected tissues. Different imaging modalities, including chest radiography, X-rays, computed tomography, magnetic resonance imaging, and (67) Ga scintigraphy are currently employed to help diagnose and help plan treatment strategy in sarcoidosis patients. Here, we discuss the potential role of positron emission tomography in the diagnosis, assessment of disease activity, and management of patients with sarcoidosis. We also point out some of the limitations of this technique.
结节病是一种多系统肉芽肿性疾病,最常表现为肺部受累。诊断基于临床和影像学表现,并通过在受累组织中组织学显示非干酪性肉芽肿得到支持。目前使用不同的成像方式,包括胸部 X 线摄影、X 射线、计算机断层扫描、磁共振成像和 (67) Ga 闪烁扫描,来帮助诊断和制定结节病患者的治疗策略。在这里,我们讨论正电子发射断层扫描在结节病患者的诊断、疾病活动评估和管理中的潜在作用。我们还指出了该技术的一些局限性。