干燥综合征患者的胃食管反流病症状与牙齿磨损。

Gastro-oesophageal reflux disease symptoms and tooth wear in patients with Sjögren's syndrome.

机构信息

King's College London Dental Institute at Guy's, King's and St Thomas' Dental Hospitals, KCL, London, UK.

出版信息

Caries Res. 2011;45(3):323-6. doi: 10.1159/000329381. Epub 2011 Jun 30.

PMID:21720160

Abstract

The aim of this study was to assess the prevalence of gastro-oesophageal reflux disease (GORD) symptoms and tooth wear in patients with Sjögren's syndrome (SS) compared with matched controls. GORD symptoms were assessed for 33 SS patients and 20 age- and sex-matched controls. Tooth wear was assessed in all patients and controls. The results were further analysed in two subgroups of SS patients and controls with and without GORD symptoms (SS patients without GORD symptoms: n = 11, controls without GORD symptoms: n = 18). A higher proportion of SS patients reported suffering from heartburn and regurgitation than controls (p < 0.001 and p = 0.02, respectively). SS patients without GORD symptoms had a statistically significantly higher percentage of surfaces with tooth wear affecting dentine than controls (p < 0.001).

摘要

本研究旨在评估干燥综合征（SS）患者与匹配对照组相比，胃食管反流病（GORD）症状和牙齿磨损的患病率。为 33 名 SS 患者和 20 名年龄和性别匹配的对照组评估了 GORD 症状。对所有患者和对照组进行了牙齿磨损评估。结果进一步在有和没有 GORD 症状的 SS 患者和对照组的两个亚组中进行分析（无 GORD 症状的 SS 患者：n = 11，无 GORD 症状的对照组：n = 18）。与对照组相比，更多的 SS 患者报告有心灼热和反流症状（p < 0.001 和 p = 0.02）。无 GORD 症状的 SS 患者的牙面磨损影响牙本质的百分比明显高于对照组（p < 0.001）。