Leung Katherine C M, McMillan Anne S, Leung W Keung, Wong May C M, Lau Chak S, Mok Temy M Y
Oral Rehabilitation, Faculty of Dentistry, University of Hong Kong, 34 Hospital Road, Hong Kong SAR, China.
Int Dent J. 2004 Jun;54(3):159-65. doi: 10.1111/j.1875-595x.2004.tb00273.x.
To investigate the oral health condition and saliva flow of southern Chinese patients with Sjögren's syndrome (SS).
51 SS patients (26 primary and 25 secondary cases) and 29 controls took part in this cross-sectional study. Stimulated whole and parotid saliva flow rates, pH, and buffer capacity, and xerostomia, oral mucosal lesions, oral hygiene status, dental and periodontal conditions, prosthetic status were assessed and compared between groups.
Stimulated whole saliva (SWS) flow was reduced in primary and secondary SS cases (p<0.001), pH and buffer capacity were also reduced in the primary SS group (p<0.05). SS patients had a greater prevalence of xerostomia than controls (p<0.001). Primary SS patients had a higher mean DMFT, more missing teeth, and more prostheses than secondary SS cases and controls (p<0.05). SWS flow correlated negatively with the number of filled teeth in both SS groups (p<0.05) and the number of decayed teeth in the primary SS group (p<0.05).
Despite good oral hygiene and regular dental check-ups, the oral health of southern Chinese with primary SS was significantly compromised compared with secondary SS cases and controls, most probably due to the combined effect of impaired salivary gland function and poorer saliva buffer capacity.
调查中国南方干燥综合征（SS）患者的口腔健康状况和唾液流量。
51例SS患者（26例原发性和25例继发性）和29例对照参与了这项横断面研究。评估并比较了两组之间刺激后的全唾液和腮腺唾液流速、pH值、缓冲能力，以及口干、口腔黏膜病变、口腔卫生状况、牙齿和牙周情况、修复状况。
原发性和继发性SS患者刺激后的全唾液（SWS）流量均降低（p<0.001），原发性SS组的pH值和缓冲能力也降低（p<0.05）。SS患者口干的患病率高于对照组（p<0.001）。原发性SS患者的平均龋失补牙数（DMFT）更高，缺牙更多，假牙比继发性SS患者和对照组更多（p<0.05）。SWS流量与两组SS患者的补牙数均呈负相关（p<0.05），与原发性SS组的龋齿数呈负相关（p<0.05）。
尽管口腔卫生良好且定期进行牙齿检查，但与继发性SS患者和对照组相比，中国南方原发性SS患者的口腔健康仍受到显著损害，这很可能是由于唾液腺功能受损和唾液缓冲能力较差的综合作用所致。
