坦桑尼亚新生儿中的巴氏血红蛋白

Haemoglobin Barts in newborn Tanzanians.

作者信息

Nhonoli A M, Kujwalile J M, Mmari P W, Shemaghoda Y

出版信息

Acta Haematol. 1979;61(2):114-9. doi: 10.1159/000207641.

DOI:10.1159/000207641

Abstract

Using both starch gel and cellulose-acetate electrophoresis is screening procedures, haemoglobin (Hb) Barts was detected in 11.08% of 325 cord blood samples from newborn Tanzanians. Red cell studies in these and in normals and a search for inclusion bodies of Hb H did not suggest alpha-thalassaemia. The mothers of these babies do not show any evidence of alpha-thalassaemia. It is suggested that the presence of Hb Barts in samples of cord blood is not due to the presence of alpha-thalassaemia in the Tanzanian population.

摘要

采用淀粉凝胶电泳和醋酸纤维素电泳两种筛查方法，在325例坦桑尼亚新生儿脐带血样本中，11.08%检测到血红蛋白（Hb）巴氏。对这些样本以及正常样本进行红细胞研究，并寻找Hb H包涵体，结果均未提示α地中海贫血。这些婴儿的母亲也未显示出任何α地中海贫血的迹象。提示脐带血样本中Hb巴氏的存在并非由于坦桑尼亚人群中存在α地中海贫血。