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一例四肢瘫痪伴肌阵挛性运动患者的神经纤维变性

Neurofibrillary degeneration in a case of quadriplegia and myoclonic movement.

作者信息

Kuroda S, Otsuki S, Tateishi J, Hirano A

出版信息

Acta Neuropathol. 1979 Feb 15;45(2):105-9. doi: 10.1007/BF00691887.

DOI:10.1007/BF00691887
PMID:217225
Abstract

A case of spastic quadriplegia with myoclonic movement was studied by both light and electron microscope. Argentophilic inclusions were found in a unique distribution involving the cerebral cortex, brain stem, cerebellum, and the spinal cord, including the motor neuron system. The fine structure of the inclusions consisted of accumulation of previously undescribed straight or wavy tubules approximately 120A wide devoid of periodic constriction.

摘要

对一例伴有肌阵挛运动的痉挛性四肢瘫痪病例进行了光镜和电镜研究。在大脑皮层、脑干、小脑和脊髓(包括运动神经元系统)中发现了具有独特分布的嗜银包涵体。这些包涵体的精细结构由以前未描述过的、宽度约为120埃的直的或波浪状小管聚集而成,没有周期性收缩。

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本文引用的文献

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EXPERIMENTAL PRODUCTION OF NEUROFIBRILLARY DEGENERATION 2. ELECTRON MICROSCOPY, PHOSPHATASE HISTOCHEMISTRY AND ELECTRON PROBE ANALYSIS.神经原纤维变性的实验性产生2. 电子显微镜检查、磷酸酶组织化学和电子探针分析
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PROGRESSIVE SUPRANUCLEAR PALSY. A HETEROGENEOUS DEGENERATION INVOLVING THE BRAIN STEM, BASAL GANGLIA AND CEREBELLUM WITH VERTICAL GAZE AND PSEUDOBULBAR PALSY, NUCHAL DYSTONIA AND DEMENTIA.
进行性核上性麻痹。一种涉及脑干、基底神经节和小脑的异质性变性,伴有垂直凝视和假性延髓麻痹、颈部肌张力障碍和痴呆。
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THE FINE STRUCTURE OF NEUROFIBRILLARY TANGLES IN ALZHEIMER'S DISEASE.阿尔茨海默病中神经原纤维缠结的精细结构
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Alzheimer's neurofibrillary changes. A topographic study.阿尔茨海默病神经纤维变化。一项地形学研究。
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Experimental colchicine encephalopathy. I. Induction of neurofibrillary degeneration.实验性秋水仙碱脑病。I. 神经原纤维变性的诱导
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Intraneuronal conglomerates in sporadic motor neuron disease. A light and electron microscopic study.散发性运动神经元病中的神经元内聚集体:光镜与电镜研究
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J Neuropathol Exp Neurol. 1968 Oct;27(4):645-58.
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