Department of Genetics, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, 14049-900, Ribeirão Preto, São Paulo, Brazil.
J Anim Sci. 2011 Nov;89(11):3410-25. doi: 10.2527/jas.2010-3520. Epub 2011 Jul 1.
The interest in the effect of genotype × environment interaction is increasing because animal breeding programs have become geographically broader. Climate changes in the next decades are also expected to challenge the present breeding goals, increasing the importance of environmental sensitivity. The aim of this work was to analyze genotype × environment interaction effect on cattle BW using the environmental sensitivity predicted by random regression reaction norm models, including sex and age effects as additional dimensions in the study. Genetic parameters were estimated for adjusted BW of Brazilian Nelore cattle at different ages (120, 210, 365, and 450 d), using linear polynomials for random regression analysis. The analyses with sex as a fixed effect (total analyses) were compared with those with sex-separated progenies (male and female progeny analyses, respectively). (Co)variance components were estimated and breeding values calculated EPD. The results showed important differences in reaction norm model genetic parameter estimates according to different age and sex analyses. The results confirmed the presence of an important genotype × environment × sex × age interaction for Nelore cattle BW. The patterns in these results lead to a revision of the importance of sexual and developmental factors on plasticity and adaptation concepts.
由于动物育种计划的地理范围越来越广，基因型与环境互作的影响引起了越来越多的关注。预计未来几十年的气候变化也将挑战当前的育种目标，从而增加环境敏感性的重要性。本研究的目的是使用随机回归反应规范模型预测的环境敏感性来分析牛体重（BW）的基因型与环境互作效应，其中包括性别和年龄效应作为研究的附加维度。使用线性多项式进行随机回归分析，估计了不同年龄（120、210、365 和 450 天）巴西内罗尔牛调整后 BW 的遗传参数。对性别作为固定效应的分析（总分析）与性别分离后代的分析（雄性和雌性后代分析，分别）进行了比较。（协）方差分量进行了估计，并计算了 EPD 的育种值。结果表明，根据不同的年龄和性别分析，反应规范模型遗传参数估计值存在重要差异。结果证实了内罗尔牛 BW 存在重要的基因型与环境与性别与年龄互作。这些结果的模式导致对可塑性和适应性概念中性别和发育因素的重要性进行了修订。
