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在基线时年龄为 61-63 岁的人群中习惯性打鼾和不安腿综合征的 10 年自然病程。

Ten-year natural course of habitual snoring and restless legs syndrome in a population aged 61-63 years at the baseline.

机构信息

Institute of Health Sciences, University of Oulu, Oulu, Finland.

出版信息

Sleep Breath. 2012 Sep;16(3):639-48. doi: 10.1007/s11325-011-0551-8. Epub 2011 Jul 3.

Abstract

PURPOSE

We investigated the prevalence, natural course, and associated risk factors of habitual snoring (HS) and restless legs syndrome (RLS) over a period of 10 years among an aging population from their early sixties to their seventies.

METHODS

A population-based follow-up study among all persons born in 1935 and living in the city of Oulu in northern Finland was conducted. In this study, we examined subjects who had participated in two subsequent surveys conducted in 1996-1998 and 2007-2008. The data were gathered by questionnaires, as well as by laboratory and clinical measurements.

RESULTS

Altogether 457 (55%) of the 838 eligible subjects participated in both surveys. The prevalence of both RLS and HS decreased during the 10 years from 21% to 15% and from 26% to 19%, respectively. Half of those who snored in 1996-1998 stopped snoring in 10 years time, and half of those who suffered from restless legs at least three times per week in 1996-1998 suffered from this syndrome never or less than once a week in 2007-2008. The 10-year incidence of new cases of both HS and RLS was 7%. Male gender predicted best the incidence of new HS in 10 years, while the Zung sum score as a marker of depressive symptoms and waist circumference predicted RLS.

CONCLUSIONS

Overall, the prevalence of both HS and RLS seems to diminish during aging. The causes behind this still remain unknown and should be investigated with more sophisticated methods.

摘要

目的

我们研究了一个从 60 多岁到 70 多岁的老年人群体中,习惯性打鼾(HS)和不宁腿综合征(RLS)在 10 年内的流行率、自然病程和相关危险因素。

方法

在芬兰北部奥卢市进行了一项基于人群的随访研究,研究对象为所有出生于 1935 年且居住在该市的人群。在这项研究中,我们检查了参加了 1996-1998 年和 2007-2008 年两次后续调查的受试者。数据通过问卷调查、实验室和临床测量收集。

结果

在 838 名符合条件的受试者中,共有 457 名(55%)参加了两次调查。在 10 年内,RLS 和 HS 的患病率分别从 21%降至 15%和从 26%降至 19%。在 1996-1998 年打鼾的人中,有一半在 10 年内停止了打鼾,而在 1996-1998 年每周至少有三次不宁腿症状的人中,有一半在 2007-2008 年没有或每周少于一次出现这种综合征。新发生 HS 和 RLS 的 10 年发病率分别为 7%。男性性别预测了新发生 HS 在 10 年内的最佳发病率,而 Zung 总分作为抑郁症状的标志物和腰围预测了 RLS。

结论

总体而言,随着年龄的增长,HS 和 RLS 的患病率似乎有所下降。其背后的原因尚不清楚,应采用更复杂的方法进行研究。

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