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动态薄层CT在肺癌淋巴结转移检测中的应用价值

[Usefulness of dynamic thin section CT in detecting lymph node metastasis of lung cancer].

作者信息

Miyamoto H, Hata E, Hayakawa K, Sato Y, Rennekampff H O, Fukuda H, Mori K, Ibukuro K, Sato S, Inoue Y

机构信息

Department of Surgery, Mitsui Memorial Hospital.

出版信息

Kyobu Geka. 1990 Aug;43(9):701-6.

PMID:2172610
Abstract

The diagnosis for metastatic lymph nodes of lung cancer by the conventional CT is done only by the size of nodes, therefore, its diagnostic accuracy is questionable. For the purpose of more qualitative diagnosis in order to elevate accuracy of metastatic nodes, we studied a new CT image (Dynamic Thin Section CT) by combining the Thin Section CT with the Dynamic CT, and reviewed on the image of histopathological positive nodes. Firstly, for the preoperative cases of lung cancer, the conventional CT was performed for the whole chest with 10 mm-thickness and 10 mm-interval. Secondary, among them, the Dynamic CT by bolus-injection at the sites of detected hilar and mediastinal lymph nodes was performed. For this method, the Thin Section CT with 2 mm-thickness was used, and the image-detected nodes were isolated by surgery. We studied 25 cases whose images were compared with the histological findings. By the conventional CT sensitivity were 35.7%, specificity 54.5%, and accuracy 44.0%, in regarding the shorter diameter over 1 cm as positive nodes, then under diagnosis were 36%, over diagnosis 20%. Morphological features were reviewed on the image of metastatic lymph nodes in the Dynamic Thin Section CT, and were (1) lump-like lymph nodes, (2) disappearance of the fatty plane around the lymph nodes or uneven and irregular margins, (3) irregular internal structures of enhanced lymph nodes. Moreover, small lymph nodes were clearly detected, and the size was exactly measured.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

传统CT对肺癌转移性淋巴结的诊断仅依据淋巴结大小,因此其诊断准确性存疑。为了进行更具定性的诊断以提高转移性淋巴结的诊断准确性,我们通过将薄层CT与动态CT相结合,研究了一种新的CT图像(动态薄层CT),并对组织病理学阳性淋巴结的图像进行了回顾。首先,对于肺癌术前病例,进行全胸常规CT扫描,层厚10mm,层间距10mm。其次,在其中检测到肺门和纵隔淋巴结部位进行团注动态CT扫描。此方法采用2mm层厚的薄层CT,手术分离图像检测到的淋巴结。我们研究了25例病例,将其图像与组织学结果进行比较。以短径超过1cm为阳性淋巴结,传统CT的敏感性为35.7%,特异性为54.5%,准确性为44.0%,漏诊率为36%,误诊率为20%。回顾动态薄层CT上转移性淋巴结的形态学特征,包括(1)肿块样淋巴结,(2)淋巴结周围脂肪平面消失或边缘不均匀、不规则,(3)强化淋巴结内部结构不规则。此外,小淋巴结能被清晰检测到,且大小能被精确测量。(摘要截选于250词)

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