Department of Dermatology, Kempegowda Institute of Medical Sciences, Bangalore, India.
Indian J Dermatol Venereol Leprol. 2011 Jul-Aug;77(4):498-502. doi: 10.4103/0378-6323.82413.
Generalized eruptive histiocytosis (GEH) is a rare cutaneous histiocytosis that mainly affects adults and presents with multiple symmetric papules on face, trunk, and proximal extremities. GEH is included in type IIa (histiocytes involving cells of dermal dendrocyte lineage) of histiocytic disorders. Clinical and pathological correlations are required for differentiating GEH from other histiocytic disorders and from lepromatous leprosy which clinically mimic GEH and is prevalent in India. We report a case of a middle-aged woman who presented with generalized asymptomatic papules and nodules and was treated for leprosy but was finally diagnosed to have GEH after clinical, histopathological, and immunohistochemical correlation. Furthermore, the newer lesions also showed features of progressive nodular histiocytosis.
全身性发疹性组织细胞增生症（GEH）是一种罕见的皮肤组织细胞增生症，主要影响成年人，表现为面部、躯干和近端肢体多发性对称丘疹。GEH 属于组织细胞疾病 IIa 型（组织细胞累及真皮树突状细胞谱系细胞）。为了将 GEH 与其他组织细胞疾病以及临床上类似 GEH 的瘤型麻风（在印度流行）区分开来，需要进行临床和病理相关性分析。我们报告了一例中年女性患者，表现为全身性无症状丘疹和结节，曾被误诊为麻风病进行治疗，但最终通过临床、组织病理学和免疫组织化学相关性检查被诊断为 GEH。此外，新出现的病变也表现为进行性结节性组织细胞增生症的特征。
