Keller K M, Bambauer C, Wirth S, Queisser-Luft A, Falke D, Baumann W
Kinderklinik, Johannes-Gutenberg-Universität Mainz.
Monatsschr Kinderheilkd. 1990 Sep;138(9):611-4.
306 children who received polytransfusion or exchange transfusion between 1979 and 1983 and 104 age-matched controls were re-examined at a median age of 2.9 years for hepatitis A and B, CMV, EBV, and HIV infections. This retrospective study revealed no differences between transfused children and controls. HBsAg and anti-HIV were not detected. Two children were suspected of having hepatitis C. In both groups the incidence of positive CMV and EBV serologies was significantly increased in children from Mediterranean countries. Red cell concentrates were less frequently associated with CMV infection. These results confirm the exclusive recruitment of volunteer donors from a "healthy", mainly rural population and support the preferred use of red cell concentrates in paediatric patients.
对1979年至1983年间接受多次输血或换血治疗的306名儿童以及104名年龄匹配的对照儿童，在中位年龄2.9岁时重新进行了甲型和乙型肝炎、巨细胞病毒（CMV）、EB病毒（EBV）及人类免疫缺陷病毒（HIV）感染情况的检查。这项回顾性研究显示，接受输血的儿童与对照儿童之间并无差异。未检测到乙肝表面抗原（HBsAg）和抗HIV。两名儿童疑似感染丙型肝炎。在两组中，来自地中海国家的儿童CMV和EBV血清学检测呈阳性的发生率显著增加。红细胞浓缩液与CMV感染的关联较少。这些结果证实了仅从“健康”的、主要为农村人口中招募志愿供血者，并支持在儿科患者中优先使用红细胞浓缩液。
