von Groote-Bidlingmaier Florian, Diacon Andreas H
Division of Pulmonology, Department of Medicine, Stellenbosch Universität, Kapstadt, Südafrika.
Ther Umsch. 2011 Jul;68(7):395-401. doi: 10.1024/0040-5930/a000183.
Tuberculosis is the second most common cause of death from an infectious disease after HIV/AIDS and the leading cause of death from an infectious disease in HIV-co-infected patients. Currently, drug susceptible TB is treated with a four drug regimen given over a period of two months followed by two drugs for four months. Drug resistant tuberculosis requires more complex and longer treatment with alternative substances. New antituberculosis drugs are currently being developed and investigated and are urgently needed to treat drug susceptible and drug resistant TB.
结核病是仅次于艾滋病毒/艾滋病的第二大常见传染病死因，也是合并感染艾滋病毒患者中传染病的主要死因。目前，对药物敏感的结核病采用为期两个月的四种药物联合治疗方案，随后再用两种药物治疗四个月。耐药结核病需要使用替代药物进行更复杂、更长时间的治疗。目前正在研发和研究新型抗结核药物，治疗药物敏感和耐药结核病迫切需要这些新药。
