Belec L, Tayot J, Tron P, Mikol J, Scaravilli F, Gray F
Département de Pathologie (Neuropathologie), Hôpital Henri Mondor, Créteil, France.
Neuropediatrics. 1990 Aug;21(3):124-9. doi: 10.1055/s-2008-1071477.
A female infant born pre-term to a HIV seropositive mother presented at birth with seropositivity for HIV and CMV viruria. At five months of age she developed an AIDS-related complex. Six months later she died from rapidly progressive diffuse encephalopathy. Post mortem examination revealed generalized CMV infection. Neuropathological examination showed a nodular encephalitis with occasional cytomegalic cells containing characteristic CMV inclusion bodies. There was no evidence of HIV encephalitis; immunostaining for HIV antigen (gp 41) was negative. Opportunistic infections in infants with congenital AIDS are the exception. To our knowledge, only one case of CMV encephalitis in an infant with congenital AIDS has been reported previously. In that case, as in the present one, a reactivation of a congenital CMV infection is likely.
一名早产女婴，其母亲为HIV血清反应阳性，出生时HIV血清反应呈阳性且有巨细胞病毒（CMV）病毒尿症。五个月大时，她患上了艾滋病相关综合征。六个月后，她死于快速进展的弥漫性脑病。尸检显示全身性CMV感染。神经病理学检查显示为结节性脑炎，偶尔可见含有特征性CMV包涵体的巨细胞。没有HIV脑炎的证据；HIV抗原（gp 41）免疫染色为阴性。先天性艾滋病婴儿发生机会性感染是个例外。据我们所知，此前仅报道过一例先天性艾滋病婴儿患CMV脑炎的病例。在该病例中，与本病例一样，很可能是先天性CMV感染的重新激活。
