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[男性生殖器溃疡的微生物学研究。关于75例病例]

[Microbiological study of male genital ulcers. Apropos of 75 cases].

作者信息

Casin I, Bianchi A, Ramel F, Lajoie C, Chastang C, Scieux C, Ferchal F, Janier M, Morel P, Perol Y

机构信息

Service de Bactériologie-Virologie, Hôpital Saint-Louis, Paris, France.

出版信息

Pathol Biol (Paris). 1990 Sep;38(7):710-5.

PMID:2172895
Abstract

Between November 1986 and June 1987, the microbial aetiology of genital ulcers was assessed in 75 male patients attending the Sexually Transmitted Disease (STD) clinic in Hôpital Saint-Louis, Paris. Evidence of Haemophilus ducreyi was found in 18 patients (24%), Herpes simplex virus in 19 (25.3%). Syphilis was diagnosed on the basis of dark field microscopy and/or positive serology test in 19 patients (25.3%). Lymphogranuloma venereum was not diagnosed in any patient. Primary pathogens were not identified from the remaining 19 (25.3%) men. Neisseria gonorrhoea was isolated in five patients, from the ulcer in three cases, from the urethra in two. Asymptomatic urethral carriage of Chlamydia trachomatis was culture proven in seven cases. The presence of IgM antibodies to C. trachomatis at a titre greater than 40 found in 17 patients was a indication of a current chlamydial infection. Three patients (4%) were discovered to be HIV-1 positive.

摘要

1986年11月至1987年6月期间,对巴黎圣路易医院性传播疾病(STD)诊所的75名男性患者的生殖器溃疡微生物病因进行了评估。在18名患者(24%)中发现了杜克雷嗜血杆菌,19名患者(25.3%)发现了单纯疱疹病毒。19名患者(25.3%)根据暗视野显微镜检查和/或血清学检测呈阳性确诊为梅毒。未在任何患者中诊断出性病性淋巴肉芽肿。其余19名(25.3%)男性未鉴定出主要病原体。在5名患者中分离出淋病奈瑟菌,3例从溃疡中分离出,2例从尿道中分离出。7例经培养证实存在沙眼衣原体无症状尿道携带。17名患者中发现抗沙眼衣原体IgM抗体滴度大于40,表明存在当前衣原体感染。3名患者(4%)被发现为HIV-1阳性。

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