Neves Frederico Sampaio, de Almeida Dayane Araújo, Oliveira-Santos Christiano, dos Santos Jean Nunes, Toralles Maria Betânia Pereira, da Silva Maria Christina Bahiana Olympio, Campos Maria Isabela Guimarães, Crusoé-Rebello Iêda
Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
Spec Care Dentist. 2011 Jul-Aug;31(4):129-33. doi: 10.1111/j.1754-4505.2011.00195.x.
This study used panoramic radiographs to evaluate the presence of radiographic changes in the jaws of a population who had sickle cell disease (SCD). The authors compared the frequency of findings between subjects with and without SCD. Panoramic radiographs of 71 subjects with SCD (36 with HbSS and 35 with HbSC) and 52 healthy controls (HbAA) were evaluated for the presence of the following radiographic alterations: radiopaque areas, increased spacing of bony trabeculae, horizontal arrangement of bony trabeculae, and absence of mandibular canal corticalization. The control group had a significantly smaller number of all the radiographic features evaluated. Differences were not statistically significant between the groups with HbSS and HbSC, except for more trabecular spacing in the molar region in the HbSS genotype, suggesting a possible correlation between radiographic findings and disease presentation.
本研究使用全景X线片评估镰状细胞病（SCD）患者颌骨的影像学改变。作者比较了患SCD和未患SCD受试者的检查结果频率。对71例SCD患者（36例HbSS型和35例HbSC型）及52例健康对照者（HbAA型）的全景X线片进行评估，观察以下影像学改变：不透光区、骨小梁间距增加、骨小梁水平排列以及下颌管皮质化缺失。对照组所有评估的影像学特征数量明显较少。HbSS型和HbSC型组之间差异无统计学意义，但HbSS基因型磨牙区骨小梁间距更大，提示影像学表现与疾病表现之间可能存在关联。
