Sunderman F W
Ann Clin Lab Sci. 1979 Jan-Feb;9(1):1-10.
A brief historical resume is presented on the use of dithiocarbamates for the treatment of persons exposed to nickel carbonyl. The specificity of the treatment is demonstrated in an industrial accident in which four men were simultaneously exposed to nickel carbonyl vapors. Three of the men received dithiocarb within 24 hours after exposure and the fourth was hospitalized by his family physician and treated for bronchopneumonia with antibiotics and without benefit of dithiocarb. The three workmen who received dithiocarb became symptomless and returned to work within 72 hours after exposure. The fourth man who had not received dithiocarb died within five days after exposure.
本文简要回顾了二硫代氨基甲酸盐用于治疗羰基镍中毒人员的历史。在一次工业事故中，四人同时暴露于羰基镍蒸气中，从而证明了该治疗方法的特异性。其中三人在接触后24小时内接受了二硫代氨基甲酸盐治疗，第四人被其家庭医生收治，并使用抗生素治疗支气管肺炎，但未使用二硫代氨基甲酸盐。接受二硫代氨基甲酸盐治疗的三名工人无症状，并在接触后72小时内返回工作岗位。未接受二硫代氨基甲酸盐治疗的第四人在接触后五天内死亡。
