Epidermal growth factor increases cyclic AMP levels in pregnant rat mammary gland explants.
作者信息
Lavandero S, Ocaranza M P, Sapag-Hagar M
机构信息
Departamento de Bioquimica y Biologia Molecular, Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile, Santiago.
出版信息
Res Commun Chem Pathol Pharmacol. 1990 Sep;69(3):317-23.
PMID:2173084
Abstract
Addition of epidermal growth factor (EGF) to a rat mammary organ culture results in increase levels of intracellular cyclic AMP. This dose dependent EGF effect occurs at physiological concentrations of the hormone and was maximal in early and middle pregnancy.
摘要
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