Elfenbein G J, Siddiqui T, Rand K H, Graham-Pole J, Marcus R B, Mendenhall N P, Goedert T M, Wikle-Fisher T, Gross S A, Weiner R S
Department of Medicine, College of Medicine, J. Hillis Miller Health Center, University of Florida, Gainesville.
Rev Infect Dis. 1990 Sep-Oct;12 Suppl 7:S805-10. doi: 10.1093/clinids/12.supplement_7.s805.
Cytomegalovirus (CMV) interstitial pneumonia is a frequent and often fatal complication of allogeneic bone marrow transplantation. Because therapy for CMV pneumonia was, until recently, largely ineffective, prophylactic methods were explored. This study shows that the strategy of using CMV seronegative blood products for seronegative patients with seronegative donors or weekly administration of intravenous immunoglobulin for all other patients reduced the attack rate of CMV pneumonia. The results of this study are put into the perspective of previously published data.
巨细胞病毒（CMV）间质性肺炎是异基因骨髓移植常见且往往致命的并发症。由于直到最近，CMV肺炎的治疗在很大程度上仍无效，因此人们探索了预防方法。本研究表明，对于供者血清学阴性的血清学阴性患者使用CMV血清学阴性血液制品，以及对所有其他患者每周静脉注射免疫球蛋白的策略，降低了CMV肺炎的发病率。本研究结果是根据先前发表的数据进行分析的。
