Deshpande Kalyani, Jain Ashish, Sharma Ravikant, Prashar Savita, Jain Rajni
Department of Biochemistry, Dr. HS Judge Institute of Dental Sciences & Hospital, Panjab University, Sector 25, Chandigarh, India.
J Indian Soc Periodontol. 2010 Oct;14(4):207-12. doi: 10.4103/0972-124X.76917.
The main aim of this review is to update the reader with practical knowledge concerning the relationship between diabetes mellitus and periodontal diseases. Exclusive data is available on the association between these two chronic diseases till date. Articles published on this relationship often provide the knowledge of definitions of diabetes mellitus and periodontal diseases, prevalence, extent, severity of periodontal disease, complications of diabetes along with the possible underlying mechanisms. The authors reviewed human epidemiological studies, cross-sectional observations and longitudinal cohort, case control that evaluated variables exclusively over the past 30 years and the predominant findings from the "certain" articles are summarized in this review. This review clarifies certain queries such as 1) Do periodontal diseases have an effect on the metabolic control of diabetes? 2) Does diabetes act as a risk factor of periodontitis? 3) What are the possible underlying mechanisms relating the connection between these two chronic diseases? 4) What is the effect of periodontal intervention on metabolic control of diabetes? After a thorough survey of literature, it was observed that diabetes acts as a risk factor in development of periodontitis as periodontitis is significantly aggravated in patients suffering from diabetes having long term hyperglycemia. Different mechanisms underlying the association between the accelerated periodontal disease and diabetes are emerging but still more work is required. Major efforts are required to elucidate the impact of periodontal diseases on diabetes. At the same time, patients are needed to be made aware of regular periodontal maintenance schedule and oral hygiene.
本综述的主要目的是向读者更新关于糖尿病与牙周疾病之间关系的实用知识。迄今为止,关于这两种慢性疾病之间关联的独家数据是可用的。关于这种关系发表的文章通常提供糖尿病和牙周疾病的定义、患病率、牙周疾病的范围、严重程度、糖尿病并发症以及可能的潜在机制等知识。作者回顾了过去30年专门评估变量的人类流行病学研究、横断面观察和纵向队列、病例对照研究,并在本综述中总结了“确定”文章的主要发现。本综述澄清了一些问题,如:1)牙周疾病对糖尿病的代谢控制有影响吗?2)糖尿病是牙周炎的危险因素吗?3)这两种慢性疾病之间联系的可能潜在机制是什么?4)牙周干预对糖尿病代谢控制有什么影响?在对文献进行全面调查后,发现糖尿病是牙周炎发展的危险因素,因为长期高血糖的糖尿病患者的牙周炎会明显加重。加速牙周疾病与糖尿病之间关联的不同潜在机制正在浮现,但仍需要更多的研究。需要做出重大努力来阐明牙周疾病对糖尿病的影响。与此同时,需要让患者了解定期的牙周维护计划和口腔卫生。