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孕中期浸软胎儿中的巨细胞病毒:光镜和电镜下的持续性病毒包涵体

Cytomegalovirus in a macerated second trimester fetus: persistent viral inclusions on light and electron microscopy.

作者信息

Schwartz D A, Walker B, Furlong B, Breding E, Someren A

机构信息

Department of Pathology, Emory University School of Medicine, Atlanta, Ga.

出版信息

South Med J. 1990 Nov;83(11):1357-8. doi: 10.1097/00007611-199011000-00036.

DOI:10.1097/00007611-199011000-00036
PMID:2173150
Abstract

The macerated stillborn fetus represents at least one third of all perinatal deaths. Microscopic examination of these specimens is often unrewarding. We have reported a clinically unsuspected cytomegalovirus infection in a second trimester macerated fetus. Cells suggestive of CMV inclusions were identified by light microscopy, but electron microscopy confirmed the presence of viral infection and proved valuable in making the diagnosis even though necrosis was severe.

摘要

浸软死胎占所有围产期死亡的至少三分之一。对这些标本进行显微镜检查往往没有什么结果。我们报告了一例孕中期浸软死胎中临床上未被怀疑的巨细胞病毒感染。通过光学显微镜鉴定出提示巨细胞病毒包涵体的细胞,但电子显微镜证实了病毒感染的存在,并且即使坏死严重,在做出诊断方面也证明很有价值。

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引用本文的文献

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Congenital cytomegalovirus infection after recurrent infection: case reports and review of the literature.复发性感染后先天性巨细胞病毒感染:病例报告及文献复习
Eur J Pediatr. 2003 Apr;162(4):248-53. doi: 10.1007/s00431-002-1115-5. Epub 2003 Feb 13.