Fingerland A, Vonfracková A, Horacek J
Arkh Patol. 1978;40(12):16-22.
Changes in the pancreatic gland manifested by necrosis of excretory cells and marked atrophy of insulae with the loss of beta-cells producing insulin were observed experimentally in suckling mice infected with Coxsackie B1 virus. It is suggested that the above changes of the pancreas may be a model of human diseases caused by Coxsackie viruses, including a model of development of some cases of diabetes.
在感染柯萨奇B1病毒的乳鼠中进行实验观察发现,胰腺出现了变化,表现为排泄细胞坏死以及胰岛明显萎缩,产生胰岛素的β细胞丧失。有人认为,胰腺的上述变化可能是由柯萨奇病毒引起的人类疾病的一种模型,包括某些糖尿病病例发病过程的一种模型。