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重度子宫内膜异位症腹腔镜手术后尿潴留的发生率及转归——组织学能给出答案吗?

Prevalence and outcome of urinary retention after laparoscopic surgery for severe endometriosis--does histology provide answers?

作者信息

Gabriel Boris, Nassif Joseph, Trompoukis Pantelis, Lima Ana Maria, Barata Sonia, Lang-Avérous Gerlinde, Wattiez Arnaud

机构信息

Department of Gynecologic Surgery, Strasbourg University Hospital Hautepierre and CMCO, IRCAD/EITS, 1, Place de l' Hopital, 67091 Strasbourg, France.

出版信息

Int Urogynecol J. 2012 Jan;23(1):111-6. doi: 10.1007/s00192-011-1492-2. Epub 2011 Jul 6.

DOI:10.1007/s00192-011-1492-2
PMID:21732097
Abstract

INTRODUCTION AND HYPOTHESIS

Urinary retention after radical laparoscopic surgery for severe endometriosis is a clinically relevant complication. We hypothesized a relationship between the amount of resected nerves and the occurrence of urinary retention.

METHODS

We evaluated, retrospectively, a cohort of 221 patients. The expression of nerves in the resected specimens was investigated in patients with urinary retention and matched controls using standardized immunohistochemistry techniques.

RESULTS

The prevalence of urinary retention was 4.6% (n = 10). Importantly, there was no difference between cases and controls regarding the quantity of nerves in the resected specimens. The cumulative probability of 50% to overcome urinary retention was reached after 5.6 months. Age was the main risk factor for persistent retention (40.3 years with vs. 31.6 years without, p = 0.01).

CONCLUSIONS

In older endometriosis patients, surgical radicality should be balanced against preservation of organ function. There is a fairly good chance to recover, even after 6 months, which is important for patient counseling.

摘要

引言与假设

重度子宫内膜异位症行腹腔镜根治性手术后尿潴留是一种具有临床意义的并发症。我们推测切除神经的数量与尿潴留的发生之间存在关联。

方法

我们对221例患者进行了回顾性评估。采用标准化免疫组织化学技术,对尿潴留患者及其匹配的对照组切除标本中的神经表达进行了研究。

结果

尿潴留的发生率为4.6%(n = 10)。重要的是,切除标本中的神经数量在病例组和对照组之间没有差异。5.6个月后达到50%克服尿潴留的累积概率。年龄是持续性尿潴留的主要危险因素(有尿潴留者为40.3岁,无尿潴留者为31.6岁,p = 0.01)。

结论

对于老年子宫内膜异位症患者,手术的根治性应与器官功能的保留相平衡。即使在6个月后,恢复的机会也相当大,这对患者咨询很重要。

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本文引用的文献

1
Long-term urinary retention after laparoscopic surgery for deep endometriosis.腹腔镜深部子宫内膜异位症手术后长期尿潴留。
Fertil Steril. 2011 Feb;95(2):803.e9-12. doi: 10.1016/j.fertnstert.2010.07.1043. Epub 2010 Aug 24.
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Complications, pregnancy and recurrence in a prospective series of 500 patients operated on by the shaving technique for deep rectovaginal endometriotic nodules.在一项前瞻性系列研究中,对 500 例接受剃除法手术的深部直肠阴道子宫内膜异位症结节患者进行了手术并发症、妊娠和复发情况的研究。
Hum Reprod. 2010 Aug;25(8):1949-58. doi: 10.1093/humrep/deq135. Epub 2010 Jun 13.
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Laparoscopic colorectal resection for bowel endometriosis: feasibility, complications, and clinical outcome.
腹腔镜结直肠切除术治疗肠道子宫内膜异位症:可行性、并发症及临床结局
Arch Surg. 2009 Mar;144(3):234-9; discussion 239. doi: 10.1001/archsurg.2008.555.
4
Urinary complications after surgery for posterior deep infiltrating endometriosis are related to the extent of dissection and to uterosacral ligaments resection.深部浸润型子宫内膜异位症手术后的泌尿系统并发症与解剖范围及子宫骶韧带切除有关。
J Minim Invasive Gynecol. 2008 Mar-Apr;15(2):235-40. doi: 10.1016/j.jmig.2007.10.009.
5
Identification of novel antigens in blood vessels in rectovaginal endometriosis.直肠阴道内异症血管中新型抗原的鉴定
Mol Hum Reprod. 2007 Dec;13(12):875-86. doi: 10.1093/molehr/gam073. Epub 2007 Nov 6.
6
Laparoscopic colorectal resection for endometriosis.腹腔镜下子宫内膜异位症结直肠切除术
Surg Endosc. 2005 May;19(5):662-4. doi: 10.1007/s00464-004-8710-7. Epub 2005 Mar 11.
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[Laparoscopic colorectal resection for endometriosis: preliminary results].[腹腔镜下结直肠切除术治疗子宫内膜异位症:初步结果]
J Gynecol Obstet Biol Reprod (Paris). 2004 Nov;33(7):600-6. doi: 10.1016/s0368-2315(04)96600-8.
8
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9
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