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[烧伤及胃肠道糜烂性溃疡患者体液免疫和细胞免疫的纠正方法]

[Methods of correction of humoral and cellular immunity in patients with burns and erosive-ulcerative lesions of the gastrointestinal tract].

作者信息

Matchin E N, Atiasov N I, Zuev P D, Vinogradova G V

出版信息

Vestn Khir Im I I Grek. 1990 Apr;144(4):44-9.

PMID:2173228
Abstract

The levels of immunoglobulins G, IgA, M and T-rosette-forming lymphocytes were determined in parallel in 137 patients with burns. The endoscopic examination has revealed acute erosive-ulcerous lesions of the gastrointestinal tract in 48 of the patients. Interrelationship between the degree of morphological changes in the gastrointestinal tract, level of immunoglobulins G, IgA and amount of T-lymphocytes was established. It was found that against the background of complex therapy Levamisole, antioxidants, hyperbaric oxygenation facilitated most rapid recovery of the immunological status in burned patients, prevented the development of acute ulceration of the gastrointestinal tract and are considered as curative measures in their development.

摘要

对137例烧伤患者同时测定了免疫球蛋白G、IgA、M以及T淋巴细胞玫瑰花环形成水平。内镜检查发现48例患者存在胃肠道急性糜烂性溃疡病变。确定了胃肠道形态学改变程度、免疫球蛋白G和IgA水平以及T淋巴细胞数量之间的相互关系。结果发现,在左旋咪唑、抗氧化剂、高压氧综合治疗的背景下,烧伤患者的免疫状态恢复最快,可预防胃肠道急性溃疡的发生,被视为治疗其发生的有效措施。

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