Verniers D, Van Limbergen E, Leysen J, Ostyn F, Segers A
Afdeling Radiotherapie, U.Z. St. Rafaël, Leuven.
Acta Otorhinolaryngol Belg. 1990;44(1):21-6.
Chemodectomas are slowly growing tumours originating in the chemoreceptor bodies. The diagnosis is based on typical clinical symptoms and radiological investigation. CT scanning with contrast enhancement permits to establish diagnosis in most cases and gives a correct idea of tumour size, tumour extension, displacement of arteries and bone destruction. Small tympanic chemodectomas are successfully managed by surgery, without causing additional cranial nerve palsies. Surgery of larger lesions is frequently followed by a high percentage of local recurrence (greater than 50%) and important morbidity (neurologic sequelae). Our present series confirms that these tumours can successfully be treated by radiotherapy. Persisting local control rates can be obtained in more than 90% of cases with moderate doses (45-50 Gy in 5 weeks) of carefully planned radiotherapy.
化学感受器瘤是起源于化学感受器体的生长缓慢的肿瘤。诊断基于典型的临床症状和放射学检查。增强CT扫描在大多数情况下可确诊，并能准确了解肿瘤大小、肿瘤范围、动脉移位和骨质破坏情况。小型鼓室化学感受器瘤可通过手术成功治疗，且不会导致额外的颅神经麻痹。较大病变的手术治疗后局部复发率较高（超过50%）且常伴有严重的发病率（神经后遗症）。我们目前的系列研究证实，这些肿瘤可通过放射治疗成功治愈。精心计划的中等剂量（5周内45 - 50 Gy）放射治疗可使超过90%的病例获得持续的局部控制率。
