Li Yang, Wang Xin-ying, Huang Ying-chun, Liu Si-tong, Li Ning, Li Jie-shou
Research Institute of General Surgery, Nanjing General Hospital of Nanjing Military Command, PLA/Medical School of Nanjing University, Nanjing 210002, China.
Zhonghua Wai Ke Za Zhi. 2011 May 1;49(5):400-3.
To determine the accuracy of resting energy expenditure (REE) calculated by using the Harris-Benedict (HB) equation, Food and Agriculture Organization/World Health Organization/United Nations University (FAO/WHO/UNU) equations (FAO equations), Shizgal-Rosa (SR) equation and the LIU equation in patients with short bowel syndrome (SBS). In addition, to explore the relationship between measured REE and body weight, fat free mass, body cell mass, fat mass and fat mass percent.
Fourty-one SBS patients including 30 male and 11 female, aged from 18 to 60 years admitted between January 2001 and October 2010 were enrolled in this study. All patients required long-term parenteral or enteral plus parenteral nutrition support. Their mean age and mean stature were (37 ± 16) years and (164.3 ± 9.0) cm, and the average body weight and residual small intestine was (47.4 ± 9.3) kg and (52 ± 45) cm. Measured REEs and calculated REEs of SBS patients were estimated respectively by indirect calorimetry and REE equations, and then defined the difference of them. And body mass were metered by body composition analyzer.
A significant correlation was found between measured REEs (1218 ± 293) Kcal and calculated REEs from the HB equation (r = 0.588, P < 0.01), the SR equations (r = 0.591, P < 0.01), the FAO equations (r = 0.411, P < 0.01) and the LIU equation (r = 0.585, P < 0.01). In the total sample, the paired t test between measured REEs and REEs derived from the HB equation, SR equation and FAO equation showed no significant difference (P > 0.05). However, measured REEs were significantly higher than REEs calculated using the LIU equations by 14.17% (P < 0.01). There was also a significant correlation between measured REEs and body weight, fat free mass and body cell mass (r = 0.548, 0.641 and 0.581).
Indirect calorimetry is preferred when an accurate REE estimate of SBS patients is necessary. However, if this machine is not available, SR equation is recommended to use and LIU equation must be avoided. Fat free mass may be more useful than body weight in REE calculation.
确定使用哈里斯-本尼迪克特（HB）方程、联合国粮食及农业组织/世界卫生组织/联合国大学（FAO/WHO/UNU）方程（FAO方程）、希兹加尔-罗萨（SR）方程和刘方程计算的静息能量消耗（REE）在短肠综合征（SBS）患者中的准确性。此外，探讨实测REE与体重、去脂体重、体细胞量、脂肪量和脂肪量百分比之间的关系。
纳入2001年1月至2010年10月收治的41例SBS患者，其中男性30例，女性11例，年龄18至60岁。所有患者均需要长期肠外或肠内加肠外营养支持。他们的平均年龄和平均身高分别为（37±16）岁和（164.3±9.0）厘米，平均体重和残余小肠长度分别为（47.4±9.3）千克和（52±45）厘米。分别通过间接测热法和REE方程估算SBS患者的实测REE和计算REE，然后确定两者的差异。并使用人体成分分析仪测量体重。
实测REE（1218±293）千卡与HB方程（r = 0.588，P < 0.01）、SR方程（r = 0.591，P < 0.01）、FAO方程（r = 0.411，P < 0.01）和刘方程（r = 0.585，P < 0.01）计算的REE之间存在显著相关性。在总样本中，实测REE与HB方程、SR方程和FAO方程得出的REE之间的配对t检验无显著差异（P > 0.05）。然而，实测REE比使用刘方程计算的REE显著高14.17%（P < 0.01）。实测REE与体重、去脂体重和体细胞量之间也存在显著相关性（r = 0.548、0.641和0.581）。
当需要准确估算SBS患者的REE时，间接测热法是首选。然而，如果没有该设备，建议使用SR方程，必须避免使用刘方程。在REE计算中，去脂体重可能比体重更有用。
