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某些苯氧基烷基胺化合物的合成与降压活性

[Synthesis and antihypertensive activity of some phenoxyalkylamine compounds].

作者信息

Xia L, Ni P Z, Song W, Liu G Q, Qian J Q, Li P, Du F H

机构信息

China Pharmaceutical University, Naning.

出版信息

Yao Xue Xue Bao. 1990;25(2):150-3.

PMID:2173348
Abstract

Nine new compounds were synthesized and tested for their alpha-adrenoceptor affinity and antihypertensive activity together with 5 other previously reported compounds. Compounds I, IIa, IIb and IIIa showed high alpha-adrenoceptor affinity and strong antihypertensive activity.

摘要

合成了9种新化合物，并与其他5种先前报道的化合物一起测试了它们对α-肾上腺素能受体的亲和力和降压活性。化合物I、IIa、IIb和IIIa表现出高α-肾上腺素能受体亲和力和强降压活性。

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