Drug Ther Bull. 2011 Jul;49(7):78-81. doi: 10.1136/dtb.2011.02.0043. Epub 2011 Jul 6.
Eye conditions account for 2-5% of all consultations in general practice.1 One-third of these eye problems (equivalent to around 13-14 cases per 1,000 population per year) are cases of infective conjunctivitis, normally a self-limiting condition.2,3 Traditionally, topical antibacterials have been prescribed for people with acute infective conjunctivitis.4 In 2005, chloramphenicol eye drops became available over the counter (OTC) from UK pharmacies as a treatment for conjunctivitis, and there is evidence that the overall use of chloramphenicol for this indication has increased since then.5 Here we review the evidence on the efficacy of antibacterials in acute infective conjunctivitis. We also offer practical information and advice for prescribers and community pharmacists on managing patients with the condition.
在全科医疗中,眼部疾病占所有会诊病例的2%至5%。其中三分之一的眼部问题(相当于每年每1000人中有约13至14例)是感染性结膜炎病例,通常为自限性疾病。传统上,急性感染性结膜炎患者会被开具局部抗菌药物。2005年,氯霉素滴眼液在英国药店成为非处方药,用于治疗结膜炎,有证据表明自那时起,氯霉素用于该适应症的总体使用量有所增加。在此,我们回顾抗菌药物治疗急性感染性结膜炎疗效的证据。我们还为处方医生和社区药剂师提供关于管理该病患者的实用信息和建议。