Laboratory of Functional and Molecular Imaging, National Institutes of Health, Bethesda, Maryland 20892-1060, USA.
Curr Opin Neurol. 2011 Aug;24(4):386-93. doi: 10.1097/WCO.0b013e328348972a.
Recent developments in the MRI of the brain continue to expand its use in basic and clinical neuroscience. This review highlights some areas of recent progress.
Higher magnetic field strengths and improved signal detectors have allowed improved visualization of the various properties of the brain, facilitating the anatomical definition of function-specific areas and their connections. For example, by sensitizing the MRI signal to the magnetic susceptibility of tissue, it is starting to become possible to reveal the laminar structure of the cortex and identify millimeter-scale fiber bundles. Using exogenous contrast agents, and innovative ways to manipulate contrast, it is becoming possible to highlight specific fiber tracts and cell populations. These techniques are bringing us closer to understanding the evolutionary blueprint of the brain, improving the detection and characterization of disease, and help to guide treatment.
Recent MRI techniques are leading to more detailed and more specific contrast in the study of the brain.
脑部磁共振成像（MRI）的最新进展不断拓展其在基础和临床神经科学中的应用。本综述重点介绍了一些最新进展。
更高的磁场强度和改进的信号探测器使人们能够更好地观察大脑的各种特性，从而有助于确定特定功能区域及其连接的解剖定义。例如，通过使 MRI 信号对组织的磁化率敏感，开始有可能揭示皮层的层状结构并识别毫米级别的纤维束。利用外源性对比剂和创新的对比增强方法，有可能突出特定的纤维束和细胞群。这些技术使我们更深入地了解大脑的进化蓝图，提高了疾病的检测和特征描述能力，并有助于指导治疗。
脑部研究中的最新 MRI 技术正在导致更详细和更具体的对比。
