Hannon M J, Dinneen S, Yousif O, Thompson C J, Quigley E M M, O'Halloran D J
Department of Endocrinology and Metabolism, Cork University Hospital, Wilton, Cork.
Ir Med J. 2011 May;104(5):135-7.
The management of diabetic gastroparesis resistant to medical therapy is very difficult Gastric electrical stimulation (GES) is a relatively new therapeutic modality which has shown some promise in international trials. It has seen use in four patients in Ireland. Our aim was to determine if GES improved patients' outcomes in terms of duration and cost of inpatient stay and glycaemic control. We reviewed the patients' case notes and calculated the number of days spent as an inpatient with symptomatic gastroparesis pre and post pacemaker, the total cost of these admissions, and patients' average HbA1c pre and post GES. Mean length of stay in the year pre GES was 81.75 days and 62.25 days in the year post GES (p=0.89). There was also no improvement in glycaemic control following GES. GES has been ineffective in improving length of inpatient stay and glycaemic control in our small patient cohort.
对药物治疗无效的糖尿病胃轻瘫的管理非常困难。胃电刺激(GES)是一种相对较新的治疗方式,在国际试验中已显示出一些前景。它已在爱尔兰的四名患者中使用。我们的目的是确定GES在住院时间、住院费用和血糖控制方面是否能改善患者的预后。我们查阅了患者的病历,并计算了植入起搏器前后因症状性胃轻瘫住院的天数、这些住院的总费用以及GES前后患者的平均糖化血红蛋白(HbA1c)。GES前一年的平均住院时间为81.75天,GES后一年为62.25天(p = 0.89)。GES后血糖控制也没有改善。在我们这个小患者队列中,GES在改善住院时间和血糖控制方面没有效果。