Department of Chemical Engineering, Lakehead University, Thunder Bay, ON, Canada.
Carbohydr Res. 2011 Sep 27;346(13):2019-23. doi: 10.1016/j.carres.2011.06.007. Epub 2011 Jun 12.
Efficient conversion of glucose to 5-hydroxymethyl furfural (5-HMF), a platform chemical for fuels and materials, was achieved using CrCl(2) or CrCl(3) as the catalysts with inexpensive co-catalysts and solvents including halide salts in dimethyl sulfoxide (DMSO) and several ionic liquids. 5-HMF (54.8%) yield was achieved with the CrCl(2)/tetraethyl ammonium chloride system at mild reaction conditions (120°C and 1h). The 5-HMF formation reaction was found to be faster in ionic liquids than in the DMSO system. Effects of water in the reaction system, chromium valence and reaction temperature on the conversion of glucose into 5-HMF were discussed in this work.
使用 CrCl(2) 或 CrCl(3) 作为催化剂，结合廉价的共催化剂和溶剂（包括二甲基亚砜（DMSO）中的卤化物盐和几种离子液体），可以有效地将葡萄糖转化为 5-羟甲基糠醛（5-HMF），这是一种用于燃料和材料的平台化学品。在温和的反应条件（120°C 和 1h）下，CrCl(2)/四乙基氯化铵体系可获得 54.8%的 5-HMF 产率。与 DMSO 体系相比，5-HMF 的形成反应在离子液体中更快。本工作讨论了反应体系中的水、铬价态和反应温度对葡萄糖转化为 5-HMF 的影响。
