1例由光化性唇炎引起的转移性鳞状细胞癌。
A case of metastatic squamous cell carcinoma arising from actinic cheilitis.
作者信息
Kwon Na Hyun, Kim Si Yong, Kim Gyong Moon
机构信息
Department of Dermatology, St. Vincent Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
出版信息
Ann Dermatol. 2011 Feb;23(1):101-3. doi: 10.5021/ad.2011.23.1.101. Epub 2011 Feb 28.
Actinic keratosis (AK) is a common, sun-induced, pre-malignant lesion with a strong likelihood of progressing to a malignancy. The reported risk of AK progressing to squamous cell carcinoma (SCC) varies from less than 1% to 20%. Clinically, induration, pain, large size, marked hyperkeratosis, ulceration, bleeding, rapid growth, and recurrence or persistence may be markers of AK progression into SCC. The risk of SCC metastasizing ranges between 0.5% and 3%. However, SCC of the lip arising from actinic cheilitis is more prone to metastasis than cutaneous SCC, with rates of the former varying between 3% and 20%. Here we report a typical case of SCC from actinic cheilitis with metastasis to the lymph nodes during a 4-year follow-up period. To exclude SCC, we emphasize the need for regular follow-up and prompt evaluation, including careful pathologic examination for actinic cheilitis.
光化性角化病（AK）是一种常见的、由阳光引起的癌前病变，极有可能发展为恶性肿瘤。据报道，AK发展为鳞状细胞癌（SCC）的风险从不到1%到20%不等。临床上，硬结、疼痛、体积大、显著的角化过度、溃疡、出血、快速生长以及复发或持续存在可能是AK发展为SCC的标志。SCC转移的风险在0.5%至3%之间。然而，光化性唇炎引起的唇部SCC比皮肤SCC更容易发生转移，前者的转移率在3%至20%之间。在此我们报告一例典型的光化性唇炎引起的SCC病例，在4年的随访期内发生了淋巴结转移。为排除SCC，我们强调需要定期随访和及时评估，包括对光化性唇炎进行仔细的病理检查。
Zotero 插件