Sönksen P H
United Medical School, Guy's Hospital, London, UK.
Horm Res. 1990;33 Suppl 4:45-51. doi: 10.1159/000181583.
Replacement therapy in cases of hypopituitarism in the adult has improved dramatically in the last decade. After initial detailed investigation of the extent of the hormone deficiency, the replacement therapy is tailored to the particular needs of the individual. Over-replacement with glucocorticoids must be avoided. Replacement of gonadal steroids is simpler than the induction of fertility. Gonadotrophin-releasing hormone has simplified fertility induction in cases of hypothalamic origin of the disease. Altered body composition and poor quality of life reversible with GH therapy have emphasised the importance of GH in the adult.
在过去十年中，成人垂体功能减退症的替代疗法有了显著改善。在对激素缺乏程度进行初步详细检查后，替代疗法会根据个体的特殊需求进行调整。必须避免糖皮质激素过量替代。性腺类固醇的替代比诱导生育更为简单。促性腺激素释放激素简化了下丘脑源性疾病患者的生育诱导过程。生长激素（GH）治疗可逆转的身体成分改变和生活质量不佳凸显了GH在成人中的重要性。
