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经导管主动脉瓣植入术后多层螺旋 CT 早期评估爱德华兹 SAPIEN 生物瓣。

Evaluation of multislice computed tomography early after transcatheter aortic valve implantation with the Edwards SAPIEN bioprosthesis.

机构信息

Department of Radiology, Rouen University Hospital, Rouen, France.

出版信息

Am J Cardiol. 2011 Sep 15;108(6):873-81. doi: 10.1016/j.amjcard.2011.05.014. Epub 2011 Jul 7.

Abstract

Currently, imaging assessment of patients who undergo transcatheter aortic valve implantation is based mainly on echocardiography and angiography, both limited to provide a 3-dimensional evaluation of the prosthesis within the native valve. This study involved 34 patients who underwent multislice computed tomography (MSCT) after transcatheter aortic valve implantation. Prosthesis expansion and circularity, depth of implantation, apposition degree at the ventriculoaortic junction, and positioning in relation to coronary artery ostia were evaluated. Early clinical events such as aortic regurgitation and periprocedural conduction abnormalities were recorded and correlated with multislice computed tomographic findings. MSCT provided comprehensive 3-dimensional assessments of the prostheses in 31 of 34 of patients (91%). Expansion was excellent (mean expansion ratio 100.0 ± 10.4%) and increased significantly from the ventricular side to the aortic side of the prosthesis. Circular deployment was achieved in most patients and increased from the ventricular to the aortic side. Mean implantation depth was -2.4 ± 2.5 mm, associated with a low rate (12%) of permanent pacemaker implantation. Patients with a new conduction abnormalities had the deepest prosthesis implantation, associated with lesser expansion and circularity. Perfect apposition on MSCT was associated with a low rate of significant aortic regurgitation. In conclusion, MSCT is able to provide an accurate 3-dimensional evaluation of prosthesis deployment and positioning after transcatheter aortic valve implantation. Moreover, these anatomic findings correlate with the most frequent early complications (i.e., the occurrence of aortic regurgitation and conduction abnormalities).

摘要

目前,经导管主动脉瓣植入术患者的影像学评估主要基于超声心动图和血管造影术,但这两种方法都仅限于对原生瓣膜内的假体进行三维评估。本研究共纳入 34 例经导管主动脉瓣植入术后行多层螺旋 CT(MSCT)检查的患者。评估了假体的扩张和圆度、植入深度、房室结交界处的贴合程度以及与冠状动脉开口的位置关系。记录了早期临床事件(如主动脉瓣反流和围手术期传导异常),并与多层螺旋 CT 检查结果相关联。MSCT 对 34 例患者中的 31 例(91%)提供了全面的三维假体评估。扩张情况良好(平均扩张比为 100.0±10.4%),且从心室侧到主动脉侧显著增加。大多数患者实现了圆形展开,且从心室侧到主动脉侧逐渐增加。平均植入深度为-2.4±2.5mm,与较低的永久性起搏器植入率(12%)相关。发生新传导异常的患者假体植入最深,与扩张和圆度较小相关。MSCT 上完美的贴合与较低的严重主动脉瓣反流发生率相关。总之,MSCT 能够提供经导管主动脉瓣植入术后假体部署和定位的准确三维评估。此外,这些解剖学发现与最常见的早期并发症(即主动脉瓣反流和传导异常的发生)相关。

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