Institute of Biomedical Engineering and Instrumentation, Wroclaw University of Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland.
J Colloid Interface Sci. 2011 Oct 1;362(1):50-7. doi: 10.1016/j.jcis.2011.06.035. Epub 2011 Jun 21.
Photocatalytic and in situ microbial activity of the amorphous and annealed states of Ag-doped and un-doped titania were examined. Studies on their structure, morphology, composition, and the photo-absorption characteristics of these materials were performed. These results were correlated with the photocatalytic and microbial activity against methicillin resistant Staphylococcus aureus K324 (MRSA), methicillin susceptible S. aureus ATCC 25923 (MSSA), Escherichia coli PA 170, and yeasts Candida albicans ATCC 90028. The annealed powders containing anatase form of titania exhibited relatively higher photocatalytic activity,corresponding to activity against MRSA,when exposed to UV-A radiation. In comparison, amorphous powders exhibited low photoactivity and showed poor antibacterial performance against MRSA under UV-A exposure. Doping of amorphous titania with Ag resulted in an anti-MRSA effect without exposure to UV radiation. In the Ag-doped crystalline anatase samples, the size of Ag primary nanocrystallites increased, which led to the decrease in the surface concentration of Ag and detriment anti-MRSA activity.
研究了掺银和未掺银的无定形和退火状态二氧化钛的光催化和原位微生物活性。对这些材料的结构、形态、组成以及光吸收特性进行了研究。将这些结果与光催化和抗耐甲氧西林金黄色葡萄球菌 K324（MRSA）、甲氧西林敏感金黄色葡萄球菌 ATCC 25923（MSSA）、大肠杆菌 PA170 和酵母菌白色念珠菌 ATCC90028 的微生物活性进行了相关分析。含有锐钛矿形式二氧化钛的退火粉末在暴露于 UV-A 辐射时表现出相对较高的光催化活性，对应于对 MRSA 的活性。相比之下，无定形粉末在暴露于 UV-A 时表现出低的光活性和对 MRSA 的不良抗菌性能。无定形二氧化钛掺杂银会导致在不暴露于紫外辐射的情况下对 MRSA 产生抑制作用。在掺银的结晶锐钛矿样品中，Ag 初级纳米晶的尺寸增大，导致 Ag 的表面浓度降低，从而损害了对 MRSA 的抑制活性。
