Lim C, Tartaglia E, Tremblay B, Angha S, Gigou F
Service de chirurgie vasculaire et thoracique, centre hospitalier de Meaux, France.
J Mal Vasc. 2011 Jul;36(4):261-9. doi: 10.1016/j.jmv.2011.06.004. Epub 2011 Jul 13.
Major lower limb amputation in elderly patients is a dreaded event with high mortality and morbidity. Peripheral arterial disease is the nearly exclusive etiology. The aim of this retrospective study was to assess the feasibility of through-knee amputation, and the morbidity and mortality risk in the elderly (>65 years).
From January 2000 to October 2010, 65 Gritti-Stokes through-knee amputations were performed in 58 patients (30 women, 28 men; mean age 79 years). Acute limb ischemia was the most common cause (40%). The others indications were: severe peripheral arterial disease with extensive necrotic lesions (19%), diabetic foot ulcers (15%), non-healing below-knee amputation (10%) and vascular graft infection after prosthetic lower extremity bypass surgery (6%).
Overall 30-day mortality was 24% (n=14/58). Vascular morbidity was 9% (n=6/65). The mean hospital stay was 31 days (range 3 to 96). The overall healing rate was 78% (n=51/65). Conversion to above-knee amputation for failed Gritti-Stokes amputation was performed in one patient.
Gritti-Stokes amputation is feasible in the elderly with an acceptable one-month mortality and a satisfactory overall healing rate. Most amputations are necessitated by complications of acute limb ischemia. For this subpopulation, Gritti-Stokes amputation should be the standard amputation level. The data collected in this study provide important information that can be useful before amputation for this population, their families and primary care physicians. Ambulation is an important postoperative goal and a multidisciplinary approach in specialized centers is required to achieve good wound healing rates.
老年患者的下肢大截肢是一件可怕的事情,死亡率和发病率都很高。外周动脉疾病几乎是唯一的病因。这项回顾性研究的目的是评估经膝关节截肢的可行性以及老年患者(>65岁)的发病和死亡风险。
2000年1月至2010年10月,对58例患者(30例女性,28例男性;平均年龄79岁)实施了65例Gritti-Stokes经膝关节截肢手术。急性肢体缺血是最常见的原因(40%)。其他指征包括:伴有广泛坏死病变的严重外周动脉疾病(19%)、糖尿病足溃疡(15%)、膝下截肢不愈合(10%)以及下肢假体旁路手术后的血管移植物感染(6%)。
30天总死亡率为24%(n=14/58)。血管并发症发生率为9%(n=6/65)。平均住院时间为31天(范围3至96天)。总愈合率为78%(n=51/65)。1例患者因Gritti-Stokes截肢失败而改行膝上截肢。
Gritti-Stokes截肢对于老年人是可行的,其1个月死亡率可接受,总愈合率令人满意。大多数截肢是由急性肢体缺血并发症所致。对于这一亚组人群,Gritti-Stokes截肢应作为标准截肢水平。本研究收集的数据为该人群、其家属和初级保健医生在截肢前提供了重要信息。行走是一个重要的术后目标,需要在专业中心采用多学科方法以实现良好的伤口愈合率。