Fluger I, Maderová K, Simek M, Hájek R, Zapletalová J, Lonsky V
Department of Cardiac Surgery, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
Perfusion. 2011 Nov;26(6):503-9. doi: 10.1177/0267659111415891. Epub 2011 Jul 8.
When cardiopulmonary bypass (CPB) is used, the blood comes into contact with foreign surfaces. To diminish this impact, various types of biocompatibly coated surfaces have been developed. The study assessed the effects of heparin-coated CPB systems on the level and function of fibrinogen as measured by thromboelastography (TEG), as compared with non-coated systems. No statistically significant differences between both groups were revealed by comparing paired data. In our study, heparin-coated CPB circuits had no significant effect on either fibrinogen level or its function.
当使用体外循环（CPB）时，血液会与外来表面接触。为了减少这种影响，人们开发了各种具有生物相容性涂层的表面。该研究评估了与未涂层系统相比，肝素涂层CPB系统对通过血栓弹力图（TEG）测量的纤维蛋白原水平和功能的影响。通过比较配对数据，两组之间未发现统计学上的显著差异。在我们的研究中，肝素涂层的CPB回路对纤维蛋白原水平或其功能均无显著影响。
