Singapore Bioimaging Consortium, Biomedical Sciences Institutes, Singapore 138667.
Physiol Meas. 2011 Aug;32(8):1275-83. doi: 10.1088/0967-3334/32/8/017. Epub 2011 Jul 8.
We report the first measured values of conductivities for neonatal mammalian skull samples. We measured the average radial (normal to the skull surface) conductivity of fresh neonatal piglet skull samples at 1 kHz and found it to be around 30 mS m(-1) at ambient room temperatures of about 23 °C. Measurements were made on samples of either frontal or parietal cranial bone, using a saline-filled cell technique. The conductivity value we observed was approximately twice the values reported for adult skulls (Oostendorp et al 2000 IEEE Trans. Biomed. Eng. 47 1487-92) using a similar technique, but at a frequency of around 5 Hz. Further, we found that the conductivity of skull fragments increased linearly with thickness. We found evidence that this was related to differences in composition between the frontal and parietal bone samples tested, which we believe is because frontal bones contained a larger fraction of higher conductivity cancellous bone material.
我们报告了首例测量的新生哺乳动物颅骨样本电导率值。我们在 1 kHz 下测量了新鲜新生仔猪颅骨样本的平均径向(垂直于颅骨表面)电导率,在环境室温约 23°C 下发现其约为 30 mS m(-1)。使用充满生理盐水的细胞技术,在额骨或顶骨样本上进行了测量。我们观察到的电导率值大约是使用类似技术测量的成人颅骨(Oostendorp 等人,2000 年 IEEE 生物医学工程汇刊,47 卷,1487-1492 页)报告值的两倍,但频率约为 5 Hz。此外,我们发现颅骨碎片的电导率随厚度线性增加。我们有证据表明这与所测试的额骨和顶骨样本之间的组成差异有关,我们认为这是因为额骨包含更大比例的高导电性松质骨材料。