Ophthalmic Plastic Surgery, Albany Medical College, Slingerlands, New York 12159, USA.
Ophthalmic Plast Reconstr Surg. 2012 May-Jun;28(3):e62-4. doi: 10.1097/IOP.0b013e318223f6e3.
Trichoblastic fibroma (TBF), also known as trichoblastoma, small nodular type, is a rare benign cutaneous adnexal tumor that shows trichogenic (follicular) differentiation that can be mistaken clinically and histologically for basal cell carcinoma (BCC), a locally aggressive trichogenic carcinoma. As the clinical behaviors of these two follicular neoplasms are opposite from one another and their management is thus different, recognition of TBF is crucial for effective therapy. Although TBF most commonly is first seen on the face, this lesion has not previously been reported in the eyelid. In this report, we document the first case of TBF affecting the ocular adnexa and detail the histologic features that differentiate TBF from BCC.
毛母质瘤（TBF），也称为毛母细胞瘤，是一种罕见的良性皮肤附属器肿瘤，具有毛发生成（毛囊）分化，临床上和组织学上可误诊为基底细胞癌（BCC），即局部侵袭性毛源性癌。由于这两种毛囊肿瘤的临床行为相反，其治疗方法也不同，因此认识 TBF 对于有效治疗至关重要。虽然 TBF 最常见于面部，但以前在眼睑中并未报道过这种病变。在本报告中，我们记录了首例影响眼附属器的 TBF，并详细描述了将 TBF 与 BCC 区分开来的组织学特征。
