鼻息肉不含嗅觉结构。
Nasal polyps do not contain olfactory structures.
机构信息
Nuffield Department of Surgical Sciences, University of Oxford, United Kingdom.
出版信息
Rhinology. 2011 Jun;49(2):185-9. doi: 10.4193/Rhino09.171.
BACKGROUND
Nasal polyposis can lead to olfactory dysfunction, either due to physical obstruction of the olfactory cleft or physiological disruption of the olfactory neuroepithelium. Where medical therapy has failed to relieve symptoms of nasal polyposis, surgical excision can be considered. However, removal of polyps medial to the middle turbinate is controversial: some believe this will relieve physical obstruction to odourants, others state that removal here risks excising olfactory neuroepithelium.
METHODS
We stained 25 nasal polypectomy samples from the area medial to the middle turbinate with olfactory marker protein.
RESULTS
We confirmed that our staining method worked on normal olfactory tissue. However, no positive staining of nasal polyps was demonstrated.
CONCLUSION
We conclude that nasal polyps medial to the middle turbinate do not contain olfactory neurons, and surgical excision is not contraindicated.
背景
鼻息肉可导致嗅觉功能障碍，其原因要么是嗅觉裂的物理阻塞，要么是嗅神经上皮的生理破坏。如果药物治疗未能缓解鼻息肉的症状，可以考虑手术切除。然而，对于中鼻甲内侧的息肉是否切除存在争议：一些人认为这样可以解除气味物质的物理阻塞，另一些人则表示在此处切除有损伤嗅神经上皮的风险。
方法
我们用嗅觉标记蛋白对中鼻甲内侧的 25 个鼻息肉切除样本进行染色。
结果
我们证实了我们的染色方法在正常嗅组织上是有效的，但没有显示出鼻息肉的阳性染色。
结论
我们的结论是，中鼻甲内侧的鼻息肉不包含嗅神经元，因此手术切除在这里并不是禁忌。
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