Straka M
Department of Stomatology, Slovak Medical University, Bratislava, Slovakia.
Bratisl Lek Listy. 2011;112(7):416-20.
The aim of this review was to describe and determine the oral manifestation of DM and influences of periodontological treatment on DM. Diabetes mellitus (DM) is one of the most serious diseases of metabolism. Long-term consequences of hyperglycemia are very heterogeneous, and affect practically all tissues and organs of organism. Classical signs and symptoms of DM are polyphagia, polyuria, polydipsia, physical weakness, and decreased immunity against infections. Untreated and fully developed DM results in numerous complications, of which the most serious include nephropathies, retinopathies, myopathies, neuropathies, cardiovascular diseases, bad wound healing and disorders of microvascularity and macrovascularity. Oral manifestations of DM are of different types and they affect various tissues of this region. Summarizing and comparing the literature data were used to obtain these goals. From the etiopathogenetic viewpoint, we can state that the so far best-investigated oral complication is that of diabetic periodontitis and its consequences, including early teeth loss. Uncontrolled hyperglycemia deteriorates the periondontal status to the extent of developing into a clinical picture of diabetic periodontitis. On the other hand, it is to be noted that not all researchers have confirmed that the treatment of periodontitis brings about a statistically important improvement in diabetic markers, mainly HbA1c. It is necessary to continue in these studies (Ref. 34).
本综述的目的是描述和确定糖尿病的口腔表现以及牙周治疗对糖尿病的影响。糖尿病(DM)是最严重的代谢疾病之一。高血糖的长期后果非常多样,几乎会影响机体的所有组织和器官。糖尿病的典型症状和体征包括多食、多尿、多饮、身体虚弱以及抗感染免疫力下降。未经治疗且病情充分发展的糖尿病会导致众多并发症,其中最严重的包括肾病、视网膜病变、肌病、神经病变、心血管疾病、伤口愈合不良以及微血管和大血管紊乱。糖尿病的口腔表现有不同类型,且会影响该区域的各种组织。通过总结和比较文献数据来实现这些目标。从病因学角度来看,我们可以说,迄今为止研究得最充分的口腔并发症是糖尿病性牙周炎及其后果,包括早期牙齿脱落。未得到控制的高血糖会使牙周状况恶化,直至发展成糖尿病性牙周炎的临床表现。另一方面,需要注意的是,并非所有研究人员都证实牙周炎的治疗会使糖尿病指标(主要是糖化血红蛋白)在统计学上有显著改善。有必要继续进行这些研究(参考文献34)。