Department of Anatomy, Inonu University, School of Medicine, Malatya, Turkey.
Eur Rev Med Pharmacol Sci. 2011 May;15(5):538-42.
In this study, the harmful effects of formaldehyde (FA) on serum testosterone levels and epididymal sperm characteristics were investigated. In addition, possible protective effect of lavender oil was evaluated.
For this purpose, 21 adult male Wistar-Albino rats were used. The rats of group I was used as control group. The rats of group II were exposed FA (10 ppm/1 hour) for 35 days. The rats of group III inhaleted lavender oil (1 ml/1 hour) with FA.
While the testosterone levels, the epididymal sperm concentration and the progressive sperm motility were significantly decreased, the abnormal sperm rate was significantly increased in FA treated group when compared to control group. However, in group III, the epididymal sperm concentration and the progressive sperm motility were significantly increased, the abnormal sperm rate was significantly decreased in comparison with the FA treated group.
It can be expressed that serious damages occured via formaldehyde exposure in reproductive system and that the lavender oil had protective effects against these damages.
本研究旨在探讨甲醛（FA）对血清睾酮水平和附睾精子特征的有害影响，并评估薰衣草油的可能保护作用。
为此，使用了 21 只成年雄性 Wistar-Albino 大鼠。第 I 组大鼠作为对照组。第 II 组大鼠暴露于 FA（10ppm/1 小时）35 天。第 III 组大鼠在 FA 暴露的同时吸入薰衣草油（1ml/1 小时）。
与对照组相比，FA 处理组的睾酮水平、附睾精子浓度和前向精子活力显著降低，异常精子率显著升高。然而，在第 III 组中，与 FA 处理组相比，附睾精子浓度和前向精子活力显著增加，异常精子率显著降低。
可以表达的是，生殖系统暴露于甲醛会导致严重损伤，而薰衣草油对这些损伤具有保护作用。
