Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Ann Diagn Pathol. 2011 Aug;15(4):291-301. doi: 10.1016/j.anndiagpath.2011.03.005.
The grossing of breast specimens has been evolving over the past few decades. As image-guided core-needle biopsy has gradually replaced surgical biopsy in the initial assessment of breast lesions, most patients have a definitive diagnosis at the time of excision. Breast conserving therapy is now well accepted as a definitive treatment. Neoadjuvant therapy is also selected by a large number of patients. In addition, since its introduction in the 1990s, sentinel lymph node biopsy has become a standard procedure performed at the time of excision, as clinically indicated. Based on our institutional experience, practical guidelines for grossing breast excision specimens, as well as sentinel lymph nodes, are provided in this article.
过去几十年来，乳腺标本的检查一直在发展。随着影像引导下的核心针活检逐渐取代了乳腺病变的初始评估中的手术活检，大多数患者在切除时就有了明确的诊断。保乳治疗现在已被广泛接受为一种确定性治疗。新辅助治疗也被大量患者所选择。此外，自 20 世纪 90 年代引入以来，前哨淋巴结活检已成为临床指征明确时切除时的标准程序。基于我们机构的经验，本文提供了乳腺切除标本以及前哨淋巴结检查的实用指南。
