Department of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Postgrad Med J. 2011 Oct;87(1032):706-13. doi: 10.1136/pgmj.2011.118661. Epub 2011 Jul 11.
Hypertension is a chronic disorder which often entails debilitating cardiovascular and renal complications. Hypertension mostly arises as a complex quantitative trait that is affected by varying combinations of genetic and environmental factors. Secondary hypertension has been encountered with increasing frequency. The common causes of secondary hypertension include renal parenchymal disease, renal artery stenosis, primary aldosteronism, phaeochromocytoma, and Cushing's syndrome. The detection of a secondary cause is of the utmost importance because it provides an opportunity to convert an incurable disease into a potentially curable one. Early identification and treatment will provide a better opportunity for cure, prevent target organ damage, reduce socioeconomic burden and health expenditure associated with drug costs, and improve patients' quality of life. Hence, it is a condition not to be missed.
高血压是一种慢性疾病,常导致心血管和肾脏并发症,使人衰弱。高血压主要是一种复杂的数量性状,受遗传和环境因素的各种组合影响。继发性高血压的发病率不断增加。继发性高血压的常见原因包括肾实质疾病、肾动脉狭窄、原发性醛固酮增多症、嗜铬细胞瘤和库欣综合征。继发性原因的检测至关重要,因为它提供了将不可治愈的疾病转化为潜在可治愈疾病的机会。早期识别和治疗将为治愈提供更好的机会,预防靶器官损伤,降低与药物费用相关的社会经济负担和卫生支出,并提高患者的生活质量。因此,这种情况不容忽视。