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新型 PET 非织造布的一锅法制备及抗菌性能。

One-pot fabrication and antimicrobial properties of novel PET nonwoven fabrics.

机构信息

Institute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161, People's Republic of China.

出版信息

Biomed Mater. 2011 Aug;6(4):045009. doi: 10.1088/1748-6041/6/4/045009. Epub 2011 Jul 11.

Abstract

Recently, with the ever-growing demand for healthy living, more and more research is focused on materials capable of killing harmful microorganisms around the world. It is believed that designing such protective materials for hygienic and biomedical applications can benefit people in professional areas and daily life. Thus, in this paper, one novel kind of antibacterial poly(ethylene terephthalate) (PET) nonwoven fabrics was conveniently one-pot prepared, with the combined immobilization of two biological antimicrobial agents, i.e. ε-polylysine and natamycin, by using the soft methacrylate nonwoven fabrics adhesives. Then, the antimicrobial activities of the functional fabrics were investigated by using the standard shaking-flask method, showing excellent antibacterial efficiency (AE) against both Escherichia coli (8099) and Staphylococcus aureus (ATCC 6538) (AE > 99.99%) compared with untreated PET nonwoven fabrics. The anti-bioaerosol tests also showed similar trends. Meantime, scanning electron microscopy analysis indicated that the bacteria on the antibacterial PET appeared to be partly bacteriolyzed and showed much less viability than those on the pristine ones. Moreover, the long residual biocidal action of such modified PET fabrics was also evaluated, and the antibacterial activity of antibacterial fibers was unaffected by the 3 month artificially accelerated aging.

摘要

最近,随着人们对健康生活的需求不断增长,越来越多的研究集中在能够杀死世界各地有害微生物的材料上。人们相信,为卫生和生物医学应用设计这种防护材料可以使专业领域和日常生活中的人们受益。因此,在本文中,我们方便地通过使用软甲基丙烯酸酯非织造布粘合剂,一锅法制备了一种新型抗菌聚对苯二甲酸乙二醇酯(PET)非织造布,将两种生物抗菌剂ε-聚赖氨酸和纳他霉素固定在其中。然后,通过标准振摇瓶法研究了功能织物的抗菌活性,与未处理的 PET 非织造布相比,其对大肠杆菌(8099)和金黄色葡萄球菌(ATCC 6538)均表现出优异的抗菌效率(AE)(AE>99.99%)。抗生物气溶胶测试也显示出类似的趋势。同时,扫描电子显微镜分析表明,抗菌 PET 上的细菌部分发生了细菌溶解,其活力明显低于原始细菌。此外,还评估了这种改性 PET 织物的长期残留杀菌作用,抗菌纤维的抗菌活性不受 3 个月人工加速老化的影响。

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