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经广泛腔静脉血栓切除术的活体供肝移植治疗急性慢性布加综合征。

Living donor liver transplantation with extensive caval thrombectomy for acute-on-chronic Budd-Chiari syndrome.

机构信息

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.

出版信息

Surg Today. 2011 Jul;41(7):1026-8. doi: 10.1007/s00595-010-4376-z. Epub 2011 Jul 12.

DOI:10.1007/s00595-010-4376-z
PMID:21748628
Abstract

The key consideration when performing living donor liver transplantation (LDLT) in patients with Budd-Chiari syndrome (BCS) is careful management of a stenotic or occluded inferior vena cava (IVC), because it is not possible to replace the recipient stenotic or occluded IVC with donor IVC as in cadaver donor transplantation. We describe how we performed LDLT with extensive thrombectomy in a patient with acute-on-chronic BCS with a totally thrombosed retrohepatic IVC. The operation was successful and the patient remains well, with follow-up images showing a patent IVC and hepatic veins. To our knowledge, LDLT for a BCS patient with severe extensive caval thrombus has never been reported before. We consider that the successful outcome of this patient clearly demonstrates the feasibility of our technique of extensive thrombectomy, without a vessel graft, to manage a stenotic or occluded IVC in LDLT in patients with BCS.

摘要

在布加综合征(BCS)患者中进行活体肝移植(LDLT)时,关键考虑因素是仔细处理狭窄或闭塞的下腔静脉(IVC),因为不可能像在尸体供体移植中那样用供体 IVC 替代受体狭窄或闭塞的 IVC。我们描述了如何在一名慢性加急性 BCS 患者中进行 LDLT,并进行广泛血栓切除术,该患者的肝后 IVC 完全血栓形成。手术成功,患者情况良好,随访图像显示 IVC 和肝静脉通畅。据我们所知,以前从未有报道过 LDLT 治疗严重广泛腔静脉血栓形成的 BCS 患者。我们认为,该患者的成功结果清楚地表明了我们在 LDLT 中不使用血管移植物广泛血栓切除术治疗 BCS 患者狭窄或闭塞 IVC 的技术的可行性。

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本文引用的文献

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Surg Today. 2009;39(5):367-73. doi: 10.1007/s00595-008-3917-1. Epub 2009 Apr 30.
2
Twenty years of liver transplantation for Budd-Chiari syndrome: a national registry analysis.布加综合征肝移植二十年:一项国家登记分析
Liver Transpl. 2007 Sep;13(9):1285-94. doi: 10.1002/lt.21220.
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Utilization of autologous vein graft for replacement of the inferior vena cava in living-donor liver transplantation for obliterative hepatocavopathy.自体静脉移植物在活体供肝肝移植中用于治疗闭塞性肝腔病变以替代下腔静脉的应用。
Living donor liver transplantation for Budd-Chiari syndrome: Overcoming a troublesome situation.
活体供肝肝移植治疗布加综合征:克服棘手情况。
Medicine (Baltimore). 2016 Oct;95(43):e5136. doi: 10.1097/MD.0000000000005136.
4
Budd-Chiari syndrome and liver transplantation.布加综合征与肝移植
Intractable Rare Dis Res. 2015 Feb;4(1):24-32. doi: 10.5582/irdr.2014.01031.
5
Accessory hepatic vein recanalization for treatment of Budd-Chiari syndrome due to long-segment obstruction of the hepatic vein: initial clinical experience.副肝静脉再通术治疗肝静脉长段阻塞所致布加综合征:初步临床经验
Diagn Interv Radiol. 2015 Mar-Apr;21(2):148-53. doi: 10.5152/dir.2014.14128.
6
Catheter-directed thrombolytic therapy combined with angioplasty for hepatic vein obstruction in Budd-Chiari syndrome complicated by thrombosis.导管定向溶栓治疗联合血管成形术治疗布加综合征合并血栓形成所致肝静脉阻塞
Exp Ther Med. 2013 Oct;6(4):1015-1021. doi: 10.3892/etm.2013.1239. Epub 2013 Jul 30.
7
Living donor liver transplantation for Budd-Chiari syndrome with hepatic inferior vena cava obstruction after open pericardial procedures.经胸心包切开术后肝静脉阻塞型布加综合征的活体肝移植
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J Hepatol. 2006 Mar;44(3):520-8. doi: 10.1016/j.jhep.2005.12.002. Epub 2005 Dec 27.
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Surgical treatment of Budd-Chiari syndrome.
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