Department of Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
Liver Transpl. 2011 Nov;17 Suppl 3:S66-8. doi: 10.1002/lt.22377.
(1) Immunosuppression is responsible for excellent patient outcomes. (2) Immunosuppression withdrawal fails in most patients. (3) Patients who may benefit from immunosuppression withdrawal cannot currently be identified. (4) No data suggest that immunosuppression withdrawal decreases patient morbidity (ie, nephrotoxicity). (5) The minimization of immunosuppression instead of withdrawal may be adequate for improving patient outcomes.
(1) 免疫抑制是获得良好患者预后的关键。(2) 大多数患者的免疫抑制剂撤药会失败。(3) 目前无法确定哪些患者可能从免疫抑制剂撤药中获益。(4) 没有数据表明免疫抑制剂撤药会降低患者发病率（如肾毒性）。(5) 减少免疫抑制剂的使用而不是撤药，可能足以改善患者预后。
