McAdoo W G, Weinberger M H, Miller J Z, Fineberg N S, Grim C E
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202-5111.
J Hypertens. 1990 Oct;8(10):961-7. doi: 10.1097/00004872-199010000-00012.
To evaluate factors influencing hemodynamic responses to psychological and physical stress, 117 normotensive college students were studied. The standardized tests included arithmetic, Stroop word-color, mirror draw, isometric handgrip and cold pressor challenges. The responses of blood pressure and pulse during the tests were compared to the baseline measurements. All the challenges produced a significant (P less than 0.01) increase in systolic and diastolic pressure and pulse rate, with the greatest increase being seen with the isometric handgrip test. The increases in the systolic and diastolic pressure and the heart rate to the psychological stressors were highly correlated (P less than 0.001). The responses to the physical stressors were correlated for the diastolic pressure (P less than 0.01) and the heart rate (P less than 0.001), but not for the systolic pressure. The responses of the systolic and diastolic pressure, but not the heart rate, to the isometric handgrip correlated with the responses to the psychological stressors. The responses of the diastolic pressure and the heart rate, but not the systolic pressure, to the cold pressor stimulus correlated with the responses to the psychological stressors. The gender influenced the response to all the stressors with males having a greater (P less than 0.05) blood pressure response and a lesser (P less than 0.001) heart rate response than females. Black subjects had greater blood pressure responses to the cold pressor test and a greater diastolic pressure response to the handgrip, but there were no observed racial differences in the responses to the psychological stressors.(ABSTRACT TRUNCATED AT 250 WORDS)
为评估影响对心理和身体应激的血流动力学反应的因素,对117名血压正常的大学生进行了研究。标准化测试包括算术、斯特鲁普词色、镜像绘画、等长握力和冷加压挑战。将测试期间的血压和脉搏反应与基线测量值进行比较。所有挑战均使收缩压、舒张压和脉搏率显著升高(P<0.01),其中等长握力测试时升高幅度最大。收缩压和舒张压以及心率对心理应激源的升高高度相关(P<0.001)。对身体应激源的反应中,舒张压(P<0.01)和心率(P<0.001)相关,但收缩压不相关。等长握力时收缩压和舒张压的反应与心理应激源的反应相关,但心率不相关。冷加压刺激时舒张压和心率的反应与心理应激源的反应相关,但收缩压不相关。性别影响对所有应激源的反应,男性的血压反应更大(P<0.05),心率反应更小(P<0.001)。黑人受试者对冷加压测试的血压反应更大,对等长握力的舒张压反应更大,但在对心理应激源的反应中未观察到种族差异。(摘要截短于250字)