Department of Neuropsychiatry, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan.
Gen Hosp Psychiatry. 2011 Nov-Dec;33(6):640.e1-2. doi: 10.1016/j.genhosppsych.2011.03.003. Epub 2011 Apr 12.
We present a schizophrenic patient who experienced neuroleptic malignant syndrome with risperidone treatment due to variants of the CYP2D6 gene with reduced function. Clinicians need to be aware of this potential complication.
我们报告了一例因 CYP2D6 基因功能降低的变异而接受利培酮治疗的精神分裂症患者发生了神经阻滞剂恶性综合征。临床医生需要意识到这种潜在的并发症。