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[血管平滑肌纤维与自主神经系统]

[Vascular smooth muscle fibers and the autonomic nervous system].

作者信息

Philip I, Bernard C, Payen D, Tedgui A

机构信息

INSERM U 141, Hôpital Lariboisière, Paris.

出版信息

Agressologie. 1990 Apr;31(4):179-83.

PMID:2175154
Abstract

Vascular Smooth Muscle cell (V.S.M.C) plays a major role in the regulation of vasomotion. Sympathetic system play a key role in vascular smooth muscle function. Epinephrine (humoral pathway) and norepinephrine (nervous pathway) can both stimulate V.S.C.M. via delta and beta adrenergic receptors. The function of parasympathetic system is more controversial. Acetylcholine induces the release of a relaxing factor by the endothelial cell (E.D.R.F.) but it has a direct contracting effect on V.S.C.M. Neural vasodilation is also concerned by noradrenergic mechanisms.

摘要

血管平滑肌细胞(V.S.M.C)在血管运动调节中起主要作用。交感神经系统在血管平滑肌功能中起关键作用。肾上腺素(体液途径)和去甲肾上腺素(神经途径)均可通过δ和β肾上腺素能受体刺激血管平滑肌细胞。副交感神经系统的功能更具争议性。乙酰胆碱可诱导内皮细胞释放一种舒张因子(E.D.R.F.),但它对血管平滑肌细胞有直接的收缩作用。去甲肾上腺素能机制也与神经源性血管舒张有关。

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